From the Departments of Pharmacology (W.R.H., R.C.M., T.F., I.I.S., R.S.L.C., C.F.R., R.G.J.), Laboratory Animal Resources (M.D.D., W.R.A., M.P.), Biometrics (D.J.H ...

All experiments to determine IC 50 values were run with at least duplicates at each compound dilution, and all IC 50 values were averaged when determined in two or ...

Percentage of recovered sm in parentheses. S major configuration. 5 Mol% of 25-CuCl 2 complex. 20 Mol% of 25-CuCl 2 complex. ¶ In the absence of complex. ‖ 20 Mol% of 25 without CuCl 2.

The stereochemistry is one of the critical issues in the Staudinger reaction. We have proposed the origin of the stereoselectivity recently. The effects of solvents, additives, and pathways of ketene ...