How does obesity affect insulin production? Researchers are shining light on new stages of the ERK pathway. Researchers at the Tohoku University Graduate School of Medicine have uncovered a key ...

SpringWorks’ share price closed just below $45 Thursday, giving the company a market cap of almost $3.4 billion. Merck’s revelation that the current negotiations value SpringWorks at around ...

A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated ...

Cheryl (Cheri) Erk, 66, of Richmond, Virginia passed away peacefully surrounded by family on Tuesday, February 11th, 2025. She is preceded by her mother, Julia McGrath, and father, James McGrath.

ERK substrates were identified in nearly every subcellular organelle, which indicates an ability to affect diverse cellular processes, including all phases of the cell cycle, DNA replication, RNA ...

PP2A is a critical enzyme in regulating protein de-phosphorylation and its reactivation is fundamental for tumour suppression, but it has been historically hard to target. PP2A mutations are oncogenic ...

Rappta Therapeutics Oy has signed an exclusive global license agreement with Springworks Therapeutics Inc. for RPT-04402, a first-in-class molecular glue of specific protein phosphatase 2A (PP2A) ...

HELSINKI, Jan. 13, 2025 /PRNewswire/ -- Rappta Therapeutics ("Rappta"), focused on developing first-in-class anti-cancer drugs activating protein phosphatase 2A (PP2A), today announces an ...

13 January 2025, Helsinki, Finland: Rappta Therapeutics (“Rappta”), focused on developing first-in-class anti-cancer drugs activating protein phosphatase 2A (PP2A), today announces an exclusive global ...

Erk Russell’s rocking chair from the Rockwood Inn now sits in the office of former Georgia Southern athletic director Jared Benko. Benko received the chair from Loran Smith, who said that people ...

Francis J. Erk, Jr., 76, resident of Taylors, South Carolina, passed away peacefully surrounded by his family on January 19, 2023 after complications from metastatic melanoma. Born on December 16 ...