A temporally stable and cell-type-specific genetic driver library provides the means to access and manipulate neuronal lineages in the fly nervous system during development and adulthood.

Jesse Kesler had years of positive and personal memories from working as a contractor for Gene Hackman and his wife, Betsy Arakawa Hackman. The owner of MudCity Builders, who worked with the ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. TFs are key components of gene regulatory ...

The NF-κB p65, Bcl-2, and 18 S TaqMan gene expression and superscript IV reverse transcription kits were purchased from Fisher Scientific (Waltham, MA). The human CRC parental cell lines SW620 and S1, ...

We show that paGLI1 promotes GLI1 gene transcription through binding to and recruitment of the transcription factor complex FUS/P65 by interacting with paGLI1 DNA sequence. This interaction ...

Gene functional annotation was performed using Database for Annotation Visualization and Integrated Discovery (DAVID), with P <0.05 considered as significant. The p65 ChIP-Seq data is deposited in the ...

In this study, we have identified the role of HDAC3 in p65 deacetylation. HDAC3 regulates gene transcription by modulating the deacetylation of the core histones and some other nonhistone substrates ...

But gene expression can be modified in various ways ... These genes are associated with p65 peaks induced by TNF-α treatment. Interestingly, these regions are heavily methylated in cells naïve to ...

† Frontier Institute of Science and Technology and ‡ State Key Laboratory for Mechanical Behavior of Materials, Xi’an Jiaotong University, Xi’an 710049, China § Department of Biomedical Engineering, ...

Within its canonical signaling cascade, the sentinel event is generally considered to be the translocation and subsequent binding of the p65 subunit and its activation of its target gene. We recently ...