Quezon City. With the start of the academic year 2025-2026, the EcoWaste Coalition again raised the persistent problem with unauthorized and unlabeled toys sold near ...

They found that Zika virus actively suppresses an important molecule in cells, called NF-κB p65. Without NF-κB p65, dendritic cells get stuck in an immature state and cannot promote T cells to ...

Elevated CRIP1 expression induced high levels of myeloid-derived suppressor cell (MDSC) infiltration and fostered an immunosuppressive tumour microenvironment. Mechanistically, we primarily showed ...

transient or substoichiometric interactions of p65/RELA with cellular proteins as they occur in living cells. Accordingly, we have a limited understanding of how exactly p65/RELA cooperates with ...

Vangl2 deficient myeloid cells exhibit enhanced phosphorylation and expression of p65, therefore, promoting the secretion of pro-inflammatory cytokines after LPS stimulation. Mechanistically, NF-κB ...

3.5. Nuclear Translocation of NF-κBp65 3.6. Phosphorylation of IKBα and NF-κB p65 in Cancer Cells To further confirm findings noted during immunofluorescence assays, we evaluated IKBα and NF-κB p65 ...

Furthermore, we find that p65-induced YAP activation is essential for maintaining the proliferation of ATL cells in vitro and in vivo. Our findings unravel the functional interplay between NF-κB and ...

Here’s how it works. Cancer cells may suddenly "reawaken" and spread throughout the body after years of lying dormant. Now, scientists may be closer to understanding why. The team also examined ...