The compounds in this invention were evaluated for their potency on Natriuretic Peptide Receptor 1 (NPR1), a receptor guanylate cyclase known to play a critical role in lowering blood pressure and ...

Y. Zhou, X.W.D., and L.Y. designed research; Y. Zhou, P.L., Yaqi Tang, J. Liu, Yaru Tang, Y. Zhuang, X.L., K.X., and Z.Z. performed research; Y. Zhou, P.L., X.W.D ...

Keratinocytes in turn, have receptors for BNP, which are called NPR1 receptors. When the BNP receptors are activated, periostin is produced and itch can be turned on. "But the interesting thing ...

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Abstract: Transformation of disease-resistant gene NPR1 to Watermelon was studied by ovary injection pathway after artificial pollination . Transgenic plants were obtained. Studies showed the ...

Researchers used two imaging and crystallography techniques to uncover the structure of a key plant defense protein called NPR1, which resembles “a gliding bird.” Credit: Xinnian Dong/HHMI/Duke ...

ANP (atrial natriuretic peptide), acting through NPR1 (natriuretic peptide receptor 1), provokes hypotension. Such hypotension is thought to be due to ANP inducing vasodilation via NPR1 in the ...

Upon pathogen infections, elevated level of SA promotes massive transcriptional reprogramming in which Non-expresser of PR genes 1 (NPR1) acts as a central hub and transcriptional coactivator in ...

2003). The NPR1 and NPR1-GFP proteins were detected using the anti-NPR1 antibody (Ding et al., 2016). Two batches of NPR1 antibodies were used. Both batches detected a specific NPR1 band, and the ...

Although atrial natriuretic peptides and brain natriuretic peptides produced in the heart control circulatory homeostasis through their common receptor, NPR1, the physiologic and pathophysiologic ...