At two years of age, Harlyn Hurford should be running around the park and playing with his much-loved dinosaurs, but instead ...

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Only the later tumor cells carry the already known duplications or alterations of the cancer genes MYC, MYCN or PRDM6 that are typical for these types of medulloblastoma. "We therefore assume that ...

Patients with high-risk neuroblastoma tend to be older than 18 months at diagnosis, have amplification of the MYCN gene, and often have metastatic disease. Their treatment involves a prolonged ...

We focus on the role of the MYCN oncogene, since aberrant expression of MYCNis very significantly associated with high-risk in all three diseases and implies that they may have a common cell-of-origin ...

However, dysregulation of MYC, such as amplification of MYCN, is associated with tumorigenesis, especially for neuroblastoma. MDM2, on the other hand, is one of the most frequently studied ...

However, dysregulation of MYC, such as amplification of MYCN, is associated with tumorigenesis, especially for neuroblastoma. MDM2, on the other hand, is one of the most frequently studied ...

Neuroblastoma (NB) childhood cancers, associated with amplification of the MYCN oncogene, present an undifferentiated phenotype and are challenging to treat. This study reports MYCN cooperation with ...

Netflix (NFLX) stock pops after the streaming giant reported better-than-expected third quarter results. Bullish investors are calling for a price hike, but Citi managing director Jason Bazinet ...

Dr Yihua Wang from the University of Southampton, a senior author on the paper said: "This research represents a pivotal advancement in our understanding of MYCN non-amplified neuroblastomas.

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