Objective UC is a chronic inflammatory disease of the colonic mucosa. Growing evidence supports a role for epithelial cell defects in driving pathology. Moreover, long-lasting changes in the ...

ConspectusN-Acetylgalactosamine (GalNAc)-type O-glycosylation is an essential posttranslational modification (PTM) that plays fundamental roles in biology. Malfunction of this PTM is exemplified by ...

The intestinal barrier serves as a boundary between the mucosal immune system in the lamina propria and the external environment of the intestinal lumen, which contains a diverse array of ...

Early childhood caries (ECC) significantly impacts the physical and mental health of children. Saliva stands as a critical model for investigating the pathogenesis of caries disease since it reflects ...

Revolutionary genomic research by Genzeva, LumaGene, RYLTI, Brigham & Women’s Hospital of Harvard University, and QIAGEN Digital Insights applied an innovative use of multiomics and biomimetic digital ...

ROCKVILLE, Md., March 29, 2024 /PRNewswire/ -- Revolutionary genomic research by Genzeva, LumaGene, RYLTI, Brigham & Women's Hospital of Harvard University, and QIAGEN Digital Insights applied an ...

Background: Radiotherapy (RT) is a key component of rectal cancer (RC) treatment, however, cases of non-response to preoperative RT in patients are very common, which is associated with ...

Abstract. Introduction: Appendiceal tumors (AT) are rare and often develop peritoneal disease (PD), with 5 year survival of 15-63% for high grade adenocarcinomas (HG) and 46-96% for low grade mucinous ...

imageimageStimulation of human intestinal organoids with serum from Systemic Lupus Erythematosus patients allowed the study of this systemic disease’s impact on the epithelial barrier and gut ...