Grasp and cut samples at the edges, so the areas of interest aren't damaged. At right is a section of mouse spleen damaged by rough handling. Many of the cells are distorted beyond recognition. There ...

This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...

spleen, and small intestine of the mice. These lipids play key roles in cholesterol transport and the breakdown of biomolecules within cellular recycling centers called lysosomes. Age-related ...

For flow cytometric analysis and sorting of the spleen, bone marrow and thymus, control IgG, anti–mouse TCRαβ, anti–mouse CD45R (or B220) and anti–mouse CD11b (Mac1), anti–mouse Sca-1 ...