Treatment with IL-36 receptor inhibitors markedly reduced MMP9 levels, correlating with clinical improvement in patients with GPP. Matrix metalloproteinase 9 (MMP9) was significantly elevated in ...

Mechanistically, we show that lactate augments TCA cycle and MMP9 generation, in part, through NF-κB activation. Finally, we report a similar lactate-mediated crosstalk between epidermis and ...

Department of Orthopaedic, Universiti Putra Malaysia, Serdang Selangor, Malaysia Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Saudi Arabia Center ...

Department of Obstetrics and Gynecology, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland Department of Allergology, Clinical Immunology and Internal ...

Materials and Methods: Between January 2016 and December 2018, the EMT phenotype-based subsets of CTCs and the expression levels of PRL-3 and MMP9 in CTCs were identified, and their clinical values in ...

Department of Orthopedic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China Background: Osteoarthritis (OA) is one of the most common age-related degenerative diseases.

Breast cancer tumor. While studying a mouse model that replicates key features of early-stage human breast cancer, the researchers discovered that a ubiquitous enzyme called MMP9 is an essential ...

This process required a protein called Mmp9, which also helps shape bone development in other organisms, including humans. Defects in how early cartilage templates morph into bone and fat may ...

Two enzymes in the NETs, called NE (neutrophil elastase) and MMP9 (matrix metalloproteinase 9), interact with a protein in tissue called laminin. In sequence, first NE then MMP9 make cuts in ...