Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Liver fibrosis is a major cause of death ...

A total of 11 target genes were identified, including BCL7B, AMHR2, FEZ2, HM13, MLXIPL, MYO1F, MED23, RBM6, SP1, RFT1, and STRA13. The PRS analysis demonstrated an increasing odds ratio for MetS ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. High fructose intake during pregnancy ...

Upstream analysis implicated the involvement of highly activated oncogenic regulators, MYC, MLXIPL, MYCN, the redox master regulator NFE2L2, and the highly inhibited LARP1, leading to oncogenic ...

Cis-regulatory sequences, such as enhancers and promoters, can control physiology by regulating access to genes affecting when and with what level of intensity the genes are expressed. The risk ...

Kulminski from Duke University, University of Pittsburgh and Washington University School of Medicine examined associations of single nucleotide polymorphisms (SNPs) of the MLXIPL lipid gene with ...

Kulminski from Duke University, University of Pittsburgh and Washington University School of Medicine examined associations of single nucleotide polymorphisms (SNPs) of the MLXIPL lipid gene with ...

This study reveals that expression of the glycolytic enzyme hexokinase 2 (HK2) in adipocytes is decreased in obesity and is associated with glucose intolerance and insulin resistance. The authors then ...

Further exploring enhancer-target interaction identified functional genes that may help explain the overall risk or benefit of anti-PD-1/PD-L1 therapy, including MLXIPL, RAF1, MPL, PAK2, DLG1. In ...

This package allows the user to create regional Manhattan plots from p-values, log(p-values), or log(Bayes Factors) with points coloured according to LD and genes ...