Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the way for improved immunotherapies.
How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...
Several pathways related to mitochondria/ATP production have also been identified including cristae formation and TCA cycle. Among mitochondrial genes, OXPHOS is shown to be impaired at multiple ...
Convincing evidence, including the image analysis pipeline, indicates that two of these compounds promote mitochondrial elongation and protect against mitochondrial fragmentation caused by chemical ...
Mitochondrial metabolism requires the chaperoned import of disulfide-stabilized proteins via CHCHD4/MIA40 and its enigmatic interaction with oxidoreductase Apoptosis-inducing factor (AIF). By ...
specifically manifesting as mitochondrial swelling, cristae distortion, and an abnormal increase in mitochondrial size. These morphological changes are typically caused by alterations in the ...
Inner membrane: Folded into structures called cristae, which increase surface area for energy production. Within the inner membrane is a fluid-like substance called the mitochondrial matrix, where the ...
Objective Although perturbations in mitochondrial function and structure have been described in the intestinal epithelium of Crohn’s disease and ulcerative colitis patients, the role of epithelial ...