An FDA-approved medication called glucarpidase could serve as an antidote to kidney toxicity in patients receiving the chemotherapy drug methotrexate ... into inactive metabolites within 15 ...
Daily oral treatment with T-614, a member of the methanesulfonanilide family of cyclo-oxygenase 2 inhibitors, might be an alternative to weekly methotrexate therapy for rheumatoid arthritis (RA).