School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, P. R. China Tianjin Key Laboratory of Therapeutic Substance of Traditional Chinese Medicine, ...

Methotrexate can be an effective and usually safe drug, but it does have a long list of dose-dependent side effects. People who have Crohn's disease typically do not receive this drug in high doses, ...

Natural ways to boost metabolism can be fun and easy. Simple things like eating more protein, high-intensity interval training, lifting weights, avoiding skipping meals, drinking the right things, ...

Objectives To investigate the effect of the L-arginine metabolism on arthritis and inflammation-mediated bone loss. Methods L-arginine was applied to three arthritis models (collagen-induced arthritis ...

Get Instant Summarized Text (Gist) A new method, "smol-seq," utilizes DNA sequencing for rapid and precise metabolite detection. It employs DNA aptamers, each with a unique barcode, to bind ...

Objective Our study aimed to explore the influence of gut microbiota and their metabolites on intracranial aneurysms (IA) progression and pinpoint-related metabolic biomarkers derived from the gut ...

Of the 32 oral anticancer drugs identified, only 25 had DDIs documented in either DIF or Micromedex. Eighteen (56.3%) candidates were listed in both compendia, and 7 (21.9%) were not found in ...

Methotrexate (MTX) is usually the first-line treatment for ... the serum metabolome and the gut microbiome before intervention with MTX. Carbohydrate metabolism, transporter systems, and protein ...

DDI candidates are the oral anticancer agents of interest in this study. A total of 32 of these drugs were identified and are collated in Table 1. Selection of oral anticancer agents was based on ...