Cancers resemble wounds. The question is why, and what does this mean? Many features of cancers – the so-called ‘Hallmarks of Cancer' ...

Managed Healthcare Executive gives C-suite executives in health plans and provider organizations news and strategies for value-driven solutions.

The poster, “ Interim Open-Label Phase 1 Results of Misetionamide (GP-2250): A Small Molecule Antineoplastic That Inhibits Three Major Transcription Factors ,” was presented by Dr. Kasi on Saturday, ...

New York City mayoral race front-runner Andrew Cuomo was forced to fend off a volley of attacks from his Democratic primary rivals in a debate.

Fox Corporation ("FOX") is affirmatively committed to the corporate value of zero tolerance for sexual harassment, race discrimination, and all other forms of discrimination prohibited by law, and a ...

MYC target gene signature has recently been reported to be associated with non-cirrhotic MASH-induced HCC (Pinyol et al, 2021). Altogether, MYC amplification is found in 6–17% of human HCC (Ally et al ...

Metabolic reprogramming is a major characteristic of ccRCC (), in part due to activation of partially overlapping transcriptional and metabolic programs controlled by HIF and MYC.Both oncoproteins ...

A MYC activation signature is seen in 67% of MM patients (Chng et al., 2011), and this signature influences the progression from monoclonal gammopathy of undetermined significance (MGUS) to MM.

Preliminary results from a phase I clinical trial show that the first in class MYC inhibitor Omomyc (OMO-103) has few side effects, is tolerable, and stabilizes disease in some patients.