Inhibition of nonsense-mediated decay turns immunologically cold tumors hot by increasing the amount of mutant RNA leading to an increase in T-cell-targetable neoantigens on the cell surface.
GMP Human VCAM-1 Protein, Fc Tag (GMP-VC1H25) is expressed in human 293 cells (HEK293) and comprises amino acids Phe25–Glu698 (Accession #P19320-1). This protein features a human IgG1 Fc tag at ...
Targeted protein degradation (TPD) is an alternative to conventional protein inhibition that is gaining attention due to advantages such as ensuring complete elimination of the target protein, reduced ...
Epigenetic inhibitors as a promising new antimalarial intervention strategy? A new study identifies an inhibitor of gene regulation that specifically kills the malaria pathogen.
Joint injury induces rapid and sustained diversification of resident and infiltrating synovial macrophage phenotypes, underpinning osteoarthritis-associated synovitis.
Making a morning routine that you can actually stick to just got easier. Learn 8 tips that our experts recommend to start your day the right way.
I had previously picked Momentous’s whey protein powder as our top recommendation, but given that it’s nearly twice as expensive as Optimum Nutrition’s (for a 1.5-pound package, even), I ...
Figure 1: Characterization of the hybrid cell vaccine ... Before electrofusion, the MHC class I expression and ploidy of the tumor cells were determined by flow cytometry. DCs were generated ...
Protein design (or protein engineering) is a technique by which proteins with enhanced or novel functional properties are created. Proteins can be engineered by rational design, which typically ...
In partnership with Rethink Ireland and the Department of Rural & Community Development, we have launched the €1.5 million Connected Communities Fund to foster inclusive, resilient communities and ...
Whey protein contains all nine essential amino acids and, as a supplement, has been studied for its role in muscle building, prevention of muscle loss, wound healing, weight control, and inflammation.
A BMI of 30 to 34.9 is considered obesity class 1, 35 to 39.9 is obesity class 2, and over 40 is obesity class 3. Having obesity is considered a risk factor for a number of health conditions, such as ...
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