Explore how cutting-edge agents like alpelisib, capivasertib, MEK and ERK inhibitors, and JAK inhibitors are reshaping the ...

Briony takes a look at the new Zotac MEK1 Mini PC - a system that promises to bring great gaming performance in a small, console sized chassis. The big question - is it really worth the £1399 asking ...

Zotac's MEK1 Gaming PC. Check out all of our CES 2018 Coverage: <a href="https://www.thinkcomputers.org/tag/ces-2018/">https://www.thinkcomputers.org/tag/ces-2018/</a ...

REC-4881 (MEK1/2): Preliminary data presented at DDW as a late-breaking oral presentation on May 4, 2025 from the ongoing Phase 1b/2 TUPELO study of REC-4881 in familial adenomatous polyposis (FAP ...

These included MEK1 and MEK2, which control a pathway called ERK involved in cellular division and survival, and MEK3 and MEK6, which regulate the p38 pathway that's involved in stress-induced ...

Gomekli is an oral small molecule designed to block MEK1 and MEK2, two proteins that play key roles in the MAPK pathway. MEK inhibitors have already been approved for treating certain cancers.

SpringWorks' Gomekli belongs to a class of drugs known as MEK inhibitor and is designed to inhibit protein types MEK1 and MEK2. "In addition to a capsule, we offer a tablet that dissolves in water ...

Gandeeva Therapeutics Inc. has divulged serine/threonine-protein kinase B-raf (BRAF)/MAP2K1 (MEK1) interaction stabilizers reported to be useful for the treatment of brain metastasis.

First-in-human study of TQB3617, a BET inhibitor in patients with relapsed/refractory hematologic malignancies. ORR, n (%), 95% CI 6 (18.8), 7.2–36.4 6 (24.0), 9.4-45.1 1 (7.1), 0.2–33.9 7 (15.2), 6.3 ...

Mirdametinib is an oral small-molecule MEK inhibitor that is designed to inhibit MEK1 and MEK2 in the MAPK pathway. This key signaling network regulates cell growth and survival and plays a role ...