scripts/ └── gen_figure.py # Script for generating dG comparison plots based on result_dG.csv uni_fep_benchmarks/ │── system_1/ │ ├── README.md # Brief description of the system │ ├── protein.pdb # ...

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Celgene Corp. has divulged proteolysis targeting chimera (PROTAC) compounds comprising an E3 ubiquitin ligase-binding moiety covalently linked to a MAP kinase-activated protein kinase 2 (MAPKAPK2; MK2 ...

In the first step of this study, which consisted of analysis of the expression of two genes related to translation (CPEB1 and CPEB4) and two associated with mRNA decay (ZFP36L2 and CNOT7), COCs were ...

Focusing on the microRNA miR-4645-5p, found within these exosomes, the research uncovers its critical role in enhancing wound healing by targeting the MAPKAPK2 pathway, thereby regulating the AKT ...

MAPK-activated protein kinase 2 (MAPKAPK2) is a serine/threonine kinase, which is involved in tumorigenesis, tumor growth, metastasis, and the inflammatory process. The clinical significance and ...

Further, genetically determined PLAU, MAPKAPK2, and MFAP2 elevated rheumatoid arthritis risk in diseases involving the breast and non-female genital tissues. Genetically determined DLK1 and ...

Xinthera Inc. has divulged pyridinones acting as MAP kinase-activated protein kinase 2 (MAPKAPK2) inhibitors reported to be useful for the treatment of autoimmune disease, cancer, fibrosis, metabolic ...

Objectives: This study aimed to find novel oxidative stress (OS)-related biomarkers of osteoporosis (OP), together with targeting the macromolecule Mitogen-activated protein kinase-activated protein ...

The web service implements a very simple REST-style API. This package makes requests by the HTTP protocol to retrieve the data. Hence, fast Internet access is required for a proper use of OmnipathR.

No potential conflict of interest relevant to this letter was reported. Gaestel M. What goes up must come down: molecular basis of MAPKAP kinase 2/3-dependent regulation of the inflammatory ...