Effects of LNA treatment in the G4-array insert cells on the levels of ... Together these shed new mechanistic light on how DNA secondary structure motifs directly control the state of 3D chromatin ...

Here’s how it works. In 2022, we reported the DNA sequences of 33 medieval people buried in a Jewish cemetery in Germany. Not long after we made the data publicly available, people started ...

We thank Dr. Donald L. Court for sharing HME6 and HME63 strains; and our colleagues Hellen Houlleberghs and Tim Harmsen for useful discussions and comments on the manuscript. This work was supported ...

While such an approach is currently developed for DNA, controlled enzymatic synthesis of XNA remains at a relative state of infancy. In order to protect the masking groups of 3′-O-modified LNA and DNA ...

The researchers came up with different terminologies for low nucleic acid content bacteria based on different research backgrounds, such as: filterable bacteria, oligotrophic bacteria, and low-DNA ...

Luciferase activity was measured using an ARVO X3 (PerkinElmer) and the Dual‐Glo Luciferase Assay System (Promega). LNA/DNA probes (PAGE grade, fasmac, Table EV4) were labeled with 32P‐γ‐ATP by means ...

Taking advantage of the finding that locked nucleic acid can suppress problematic ab initio DNA synthesis, up to million-fold amplification rates and concurrent hybridization were achieved at a ...

Injection of LNA, AAV9, and Adenovirus Vectors Into Neonatal and Adult ... The RNAs were treated with DNase I (Invitrogen) to exclude the possibility of DNA contamination. Then, cDNA was reverse ...