Niacin has long been used as an effective lipid-altering therapy, particularly for raising HDL-C and lowering triglyceride levels. In addition, niacin modestly lowers LDL-C levels. LDL-C ...

The ability of niacin to influence LDL-P is under active investigation and it appears that the beneficial effects of niacin extend beyond the traditional evaluation of the 'lipid profile.

Scientists have discovered a potential new treatment for familial hypercholesterolemia, inspired by signs seen in the Mona ...

In the 1960s, an obscure Scandinavian researcher identified a peculiar blood fat particle that became known as lipoprotein(a) ...

Structural changes in apoB-100 enhance its binding to the LDL receptor 4, shifting the particle’s role to cholesterol delivery. The authors’ structural models show that apoB-100 adopts an ...

The findings revealed that regular consumption of mixed nuts markedly enhances blood lipid profiles, leading to changes in specific lipoprotein subclasses that are associated with improved heart ...

While LDL can build up in arteries over time and ... Research has suggested that HDL particle size may play a role. What Did the Study Show? To learn about how HDL particle size affects the ...

While LDL can build up in arteries over time and ... Research has suggested that HDL particle size may play a role. To learn about how HDL particle size affects the brain, researchers tracked ...

According to the Cleveland Clinic, Lp(a) is much like the so-called bad cholesterol, LDL. However, the Lp(a) type of cholesterol is "80-90%" genetically determined. The way the Lp(a) particle is ...

The proximity ligation can be initiated only in the presence of both ApoB and cholesterol on the same LDL particle, granting the approach a high selectivity for intact LDL particles. The elevated ...