Sustained reactivation of mutant p53 drives durable anti-tumor activity across models, including KRAS co-mutant tumors FMC-220 selectively stabilizes p53 Y220C at lower doses, overcoming key ...

However, they are highly expensive, which prevents them from being adopted on a wider scale. The LC3 project intends to remedy this situation by proposing a less costly solution that would retain the ...

[Keith Chambers/Science Photo Library/Getty Images] The p53 protein plays a significant role in cell biology as it regulates the cell cycle and halts the formation of tumors. Scientists have long ...

But enthusiasts of the material, called LC3, see obstacles to its widespread production and use, especially in the U.S., where cement suppliers are only beginning to consider producing it.

In a recent study published in the Cell Reports journal, researchers assessed the impact of protein adduction on p53 tumor suppressor inhibition. Studies have shown that exposing esophageal cells ...

The Low Complexity Communication Codec – LC3 for short – will be able to transmit at much lower bitrates without dropping the audio quality we currently see with Bluetooth’s standard.

As posted by Twitter user George (via ShrimpApplePro), he enabled the LC3 codec for AirPods Max through its beta firmware. For those unfamiliar, the LC3 codec is Bluetooth’s future low-power and ...

New research led by the University of Bristol has found the protein p53 plays a key role in epithelial migration and tissue repair. The findings could improve our understanding of the processes used ...

The researchers demonstrated that when used in combination with immune checkpoint blockade (ICB), the p53 mRNA nanoparticle technology—which is similar to that used in COVID-19 vaccines—not ...

The protein expression levels were standardized relative to the level of GAPDH or PCNA or p53. Autophagic Flux Detection by mRFP-GFP-LC3 Adenovirus Transfection mRFP-GFP-LC3 adenovirus (Hanbio Co. Ltd ...