They discovered previously unknown genetic mutations in several key genes, including MYBPC3, LMNA, PKP2, and KDM5B. These genes play a role in heart muscle function, and mutations in them may ...

Histone lysine demethylase KDM5B, an important anti-tumor drug target, has been involved in several cardiovascular diseases. However, its role in heart failure remains largely unknown. In the current ...

Researchers have identified the gene KDM5B as crucial in regulating learning and memory by conducting experiments with mice. Previously linked to intellectual disabilities and autism, KDM5B’s reduced ...

The gene, called KDM5B has previously been linked to some intellectual disability disorders and autism. In the general population, some variants are also associated with reduced brain function ...

The gene, called KDM5B has previously been linked to some intellectual disability disorders and autism. In the general population, some variants are also associated with reduced brain function ...

Summary: Researchers identified a critical role for the gene KDM5B in learning and memory. Their study demonstrates that mice with reduced function of this gene exhibit significant deficits in memory ...

The oligomeric NPM1 recruited histone demethylase KDM5b to the promoter of Tsc1 (TSC complex subunit 1), the mTOR (mechanistic target of rapamycin kinase) complex inhibitor, reduced histone H3K4me3 ...

ABSTRACT: Cancer stem cells (CSCs) are tumor initiating cells within the tumor mass; that play a critical role in cancer pathogenesis. CSCs regulate cancer cell survival, metastatic potential, ...

These genes seem to have a strong effect on how our brain functions. The genes are: ADGRB2, KDM5B, GIGYF1, ANKRD12, SLC8A1, RC3H2, CACNA1A, and BCAS3. The Three Tests: EDU, RT, and VNR The ...