Shanghai Shenshi Wise Technology Co. Ltd. has identified potassium voltage-gated channel subfamily A member 3 (KCNA3) channel blockers reported to be useful for the treatment of inflammatory and ...

Salt sensitivity of blood pressure is an independent predictor of cardiovascular morbidity and mortality. The exact mechanism by which salt intake increases blood pressure and cardiovascular risk is ...

1 Department of Gynecology, General Hospital of Ningxia Medical University, Yinchuan, China 2 Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China Backgrounds: ...

Results: WGCNA showed that the pink module was most correlated with the immune score. Seven of 14 key genes (FCRL3, IFNG, KCNA3, LY9, PLA2G2D, THEMIS, and TRAT1) were significantly associated with the ...

Consortium members are listed at the end of the Article.

The burden of esophageal cancer continues to rise, and noninvasive screening tools are needed. Methylated DNA markers (MDM) assayed from plasma show promise in detection of other cancers. For ...

Voltage-gated Kv1.3 and Ca 2+-dependent KCa3.1 are the most prevalent K + channels expressed by human and rat T cells. Despite the preferential upregulation of Kv1.3 over KCa3.1 on autoantigen ...

Potassium released from dying tumour cells has now been found to suppress the activity of T cells of the immune system. Enhancing the removal of potassium from T cells restores their ability to ...

The authors note that Fig. 2 and its corresponding legend appeared incorrectly. The corrected figure and its corrected legend appear below. As a result of this correction, the authors note that on ...

How nanometer-sized proteins produce micron-scale subcellular organization is poorly understood. Here we study the spatial organization of the ras-related nuclear protein (Ran) pathway in mitosis. Our ...

Specifically, the identified genes KCNA3, KCNB2, KCNIP4, KCNJ3, and SLC24A3 are involved in what is called potassium transport. A follow-up experiment showed that new intestinal cells treated with E.