and blocks the IL4/IL13 cytokine immune receptors for triple negative breast cancer. It also develops ENV 105, an antibody therapeutic for the prostate cancer patients resistant to androgen ...

Achieved dose-dependent and durable target modulation in vivo without requiring degradation of STAT6 protein --Avoided broad JAK-mediated immune suppression --Data presented at the American Thoracic ...

The purpose of this study was to determine whether immobilizing interleukin 4 (IL4) on plasma immersion ion implantation (PIII)-activated surfaces may alter the osteo-immunoregulatory characteristics ...

Host Controlled Unclassified Information (CUI) with Higher Sensitivity: Agencies can store and process CUI that requires a higher level of protection than what is typically allowed in IL4 environments ...

Casepoint becomes the first and only data discovery platform to achieve FedRAMP High and has also earned DOD IL4, reinforcing its commitment to top security standards alongside its existing ...

Cornerstone Achieves Defense Information Systems Agency (DISA) and Department of Defense (DoD) Impact Level 4 (IL4) Provisional Authorization, Strengthening Commitment to U.S. Government Security ...

SANTA MONICA, Calif.--(BUSINESS WIRE)--Cornerstone OnDemand Inc., a leader in workforce agility solutions, today announced it has achieved Impact Level 4 (IL4) from the Defense Information Systems ...

Also helping boost Regeneron’s business is the recent approval of its Sanofi-partnered Dupixent in COPD, making the IL4 and IL13 blocker the first-ever biologic cleared for this indication.

Dupixent, a blockbuster anti-IL4-alpha antagonist, was cleared for the lung condition after Phase III trials demonstrated a 30% to 34% drop in the rate of exacerbations versus placebo. In April 2024, ...

Introduction: Extracellular vesicles (EVs) produced by IL4-polarized macrophages (Mφ) suppress inflammation by communicating microRNA-controlled immunometabolic signaling to recipient immune cells and ...