NCG-hIL2 expresses the human IL2 cytokine, and NCG-hIL15 expresses the human IL15 cytokine. When engrafted with human HSC, both strains support the growth and development of NK and T cells.

Obsidian’s lead investigational cytoTIL15™ program, OBX-115, is a novel engineered tumor-derived autologous T cell immunotherapy (tumor-infiltrating lymphocyte [TIL] cell therapy) armored with ...

Post-infusion tumor tissue demonstrated presence of IL15-expressing T cells (of CD3+: D21, 68.6%; D42, 88.4%). Importantly, median post-infusion serum levels of IL15 and IL7 were not significantly ...

Bolstered management team with hires of Chief Executive Officer and Chief Medical Officer with deep biopharmaceutical experienceAnnounced selection of IL15-superagonist as first payload to be ...

Source Reference: Bourreille A, et al "Lusvertikimab, a first-in-class IL7 receptor antagonist, in moderate to severe ulcerative colitis: results of a multicenter, randomized, placebo-controlled ...

Now it’s co-ace Shota Imanaga (hamstring) on the IL15, and I’m no longer waiting to add rookie Cade Horton. Determined to capitalize on the great start, Cubs brass should have already been on ...

SAN DIEGO, April 28, 2025 (GLOBE NEWSWIRE) -- Calidi Biotherapeutics Inc. (NYSE American: CLDI) (“Calidi”), a clinical-stage biotechnology company developing a new generation of targeted ...

Calidi Biotherapeutics Announces IL15 Superagonist as First Payload to be Delivered by Systemic Antitumor Virotherapy Platform at AACR Annual Meeting Provided by GlobeNewswire Apr 28, 2025, 5:00:00 AM ...

Calidi Biotherapeutics (NYSE American: CLDI) announced the selection of IL15 superagonist (IL15-IL15Ra) as the first therapeutic payload for its sys ...

Sandeep Singh, Andrea Bedoy, Dipmoy Nath, Kyung Hee Chang, Lauren B. Ostermann, Ivo Veletic, Christopher D. Pacheco, Po Yee Mak, Edward Ayoub, Muharrem Muftuoglu, Mahesh Basyal, Taeyun Kim, Raven ...

Bioinformatics and experimental validation have revealed 179 shared differentially expressed genes (DEGs) between chronic lymphocytic leukemia (CLL) and diffuse large B-cell lymphoma (DLBCL), ...