The 19q13.32 covers the genes IGFL2 and IGFL1, and IGFL2-AS1, a long non-coding RNA (lncRNA) that negatively regulates IGFL1 expression. 39 IGFL is a family of secreted proteins and could act as ...

aPeking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking ...

KLF5 also induces the expression of a lncRNA IGFL2-AS1 (IGFL2 Antisense RNA 1) to form a transcriptional complex with TEAD4 and promotes the IGFL1 (Insulin growth factor-like family member 1) gene ...

The expression level of IGFL1 was higher in ccRCC samples with IGFLR1-high-expression than that with IGFLR1-low-expression (0.025 vs. 0.008, p < 0.001) (Supplementary Figure S2B). However, with K-M ...