Department of Physiological Sciences and Center for Environmental and Human Toxicology, University of Florida Genetics Institute, Interdisciplinary Program in Biomedical Sciences Neuroscience, College ...

The cytochrome P450 family of enzymes, which are encoded by the CYP genes, help to maintain body homeostasis by metabolizing endogenous hormones and their biochemical intermediates. As such, CYP ...

The gonadal area for each section was measured by creating a gonadal Region of Interest (ROI) drawn manually in Fiji. The number of HSD3B positive cells (2 to 493 cells per section depending on the ...

SUPPLEMENTARY FIGURE S2 Co-immunofluorescence staining of TRPC3 (green) with the endothelial cell and germ cell marker PECAM1 (red) in the mouse testis from E11.5 to E15.5, and with the Leydig cell ...

To identify the relevant studies, databases, namely, PubMed, SciELO, Google Scholar, and Lilacs, were accessed from January 1997 to November 2022 with no constraint on the year of publication.

On day 116, an interaction between lipid x LC-PUFA x oxygen was found for cyp11a, hsd3b (steroidogenesis) and ud2a2 genes, whereas LC-PUFA and/or oxygen affected the steroid levels of ...

In addition, INH and AMH together increased the inhibitory effect on FSH-induced estradiol and progesterone production, with a concomitant downregulation of FSH-stimulated CYP19A1, HSD3B, CYP11A1, ...

1Geriatric Research, Education and Clinical Center, VA Puget Sound Health Care System, Seattle, Washington. 2Fred Hutchinson Cancer Research Center, Seattle, Washington. *Corresponding Author: Elahe A ...

ABI is converted by 3β-hydroxysteroid dehydrogenase (HSD3B) into D4-abiraterone (D4-ABI). In a previous preclinical study, D4-ABI was shown to block multiple steroidogenic enzymes and antagonize the ...

Women with polycystic ovary syndrome (PCOS) have reduced fertility and increased risk of developing type 2 diabetes. Adiponectin, an adipocyte-derived hormone, together with adipocyte size, is the ...