Back in 2015, we identified a drug that may do just that, called harmine. This drug, which occurs naturally in a number of plants around the world, blocks an enzyme in the beta cells called DYRK1A.

Ancient Saudi residents inhaled harmal smoke at home, revealing early psychoactive plant use and health practices.

A study examining the effects of harmine, a major component of ayahuasca, found that it produces no significant psychoactive effects in doses up to 500 mg. None of the participants experienced ...

Researchers at Mount Sinai have discovered how harmine-family drugs can regenerate human beta cells by converting abundant alpha cells in the pancreas, offering a scalable solution for diabetes ...

Researchers assessed whether combining psychedelics, namely DMT and harmine as two active ingredients in ayahuasca, with meditation increases mindfulness, compassion, insight, and mystical-type ...

Researchers at Mount Sinai have shown that a combination of two drugs—harmine and a glucagon-like peptide 1 receptor agonist (GLP-1RA)—can enhance the regeneration of insulin-producing ...

The research involved 40 experienced meditators (18 female and 22 male) who participated in a study over a 3-day meditation retreat, receiving either placebo or DMT-harmine. The participants ...

Researchers at Mount Sinai are developing a revolutionary pill using harmine, a DYRK1A inhibitor, to regenerate insulin-producing beta cells in the pancreas. Harmine alone tripled beta cell mass ...

In 2015, Mount Sinai researchers discovered the first such drug, called harmine. Harmine is a member of a class of drugs called DYRK1A inhibitors. In 2019 and 2020, the researchers reported that ...

In 2015, Mount Sinai researchers discovered the first such drug, called harmine. Harmine is a member of a class of drugs called DYRK1A inhibitors. In 2019 and 2020, the researchers reported that ...

thanks to its production of the alkaloids harmine and harmaline. Since then Tanasi has expanded his analysis, resulting in this latest paper. Along with co-authors from the University of Trieste ...

Meditators who received a combination of DMT and harmine reported greater mystical experiences, non-dual awareness, emotional breakthroughs, and lasting increases in well-being compared to those given ...