For roughly one in every hundred people, food containing even the smallest amounts of gluten can deliver a gutful of hurt and ...

Gluten-stimulated interleukin-2 (IL-2) secretion is useful for diagnosis of celiac disease (CeD), according to a study published online June 9 in Gastroenterology. Olivia G. Moscatelli, from The ...

For patients with HLA-DQ2.5+ genetics, sensitivity was 90% and specificity was 95%, with lower sensitivity (56%) for patients with HLA-DQ8+ celiac disease. The WBAIL-2 assay correlated strongly ...

FDA Greenlights SOB100 for Phase I; Breakthrough Study Published in Nature Communications TAICHUNG, June 9, 2025 /PRNewswire/ -- A research team led by Dr. Der-Yang Cho, Superintendent of China ...

The expert informed, “Specific antibodies to test for include IgA-tTG, EMA and DGP, and genetic testing to determine HLA-DQ2 or DQ8 status is beneficial in confirming the diagnosis.

HLA-DQ2.5 is a very common genetic variant among CeD patients, representing approximately 90% of the total disease population. 1 A total of 38 patients that achieved a predefined IL-2 response to ...

Learn about celiac disease causes, symptoms, diagnosis, and gluten-free treatment options in this easy-to-understand guide.

What is coeliac disease - and what can and can’t you eat if you have it? - Just 36 per cent of people with the condition are ...

When broken-down bits of gluten are presented on the DQ2.5 variant of HLA, effector T cells react aggressively and cause celiac disease symptoms.

HLA-DQ2.5-restricted gluten-specific CD4+ T cells of a rare, uniform phenotype have been reported in CeD and connective tissue disease, and the presence of expanded T-cell clones with identical ...

The presence of the HLA-DQ8 or HLA-DQ2 proteins is a significant risk factor, though other genetic and environmental elements likely play a role. By understanding these interactions more deeply, ...