Additionally, it has been noted that solid-phase technology can detect patient antibodies against denatured HLA molecules, as well as the native HLA molecules. In essence, the anti-HLA antibodies ...

The predominant problem underlying class distinction arises from the distribution of HLA antigens. MHC class I molecules are found on all nucleated cells, whereas MHC class II molecules are ...

Inhibition of nonsense-mediated decay turns immunologically cold tumors hot by increasing the amount of mutant RNA leading to an increase in T-cell-targetable neoantigens on the cell surface.

Heart disease is the number one killer of men and women, but it often presents differently depending on sex. There are sex ...

These bars show that there is a significant increase in performance of the trans-allele method for HLA-DR molecules and decrease for HLA-DQ molecules compared with the intra-allele method. The ...

indicating key positions within HLA molecules that may confer risk. Differing associations in adult and juvenile onset disease with the same autoantibody suggests distinct aetiologies and disease ...

and three soluble (HLA-G5, -G6, and -G7) molecules have been acknowledged, and more novel isoforms remain to be validated. Multiple receptors such as (immunoglobulin-like transcripts 2/ILT2, ILT4, ...

Scientists studying samples that NASA collected from the asteroid Bennu found a wide assortment of organic molecules that shed light on how life arose. By Carl Zimmer Our solar system contains ...

Add articles to your saved list and come back to them any time. Zwitterions are strange molecules that are positive and negative at once. Sydney scientists are harnessing zwitterions to improve ...

Altogether, this results in the release of damage-associated molecular pattern (DAMP) molecules and pathogen-associated molecular pattern (PAMP) molecules, both of which activate interferon-γ ...