News-Medical.Net1d
Centauri Therapeutics selects first clinical candidate, for immunotherapeutic treatment of Gram-negative bacterial infections
Centauri Therapeutics Limited (Centauri), an immunotherapy company with a unique and proprietary platform technology ...
BioWorld1d
Centauri selects clinical candidate for gram-negative bacterial lung infections
Centauri Therapeutics Ltd. has selected its first clinical candidate in the ABX-01 program to treat gram-negative bacterial lung infections. Based on the company’s Alphamer platform, the ...
News Medical15d
Unlocking the potential of double negative memory B cells in cancer treatment
so-called because they are negative for two markers found on the surface of their more common brethren. They may also be a useful diagnostic marker when creating treatment plans. The ...
Dairy Herd16d
Extended Treatment of Gram-negative Mastitis
“Until now, no research has so vividly demonstrated treatment success of mastitis infections caused by Gram-negative bacteria like E. coli,” says Roger Saltman, DVM, MBA, Group Director, Pfizer Animal ...
National Institute for Health and Care Excellence29d
Elacestrant for treating oestrogen receptor-positive HER2-negative advanced breast cancer with an ESR1 mutation after endocrine treatment
This recommendation is not intended to affect treatment with elacestrant that was started in the NHS before this guidance was published. People having treatment outside this recommendation may ...
National Institute for Health and Care Excellence29d
Elacestrant for treating oestrogen receptor-positive HER2-negative advanced breast cancer with an ESR1 mutation after endocrine treatment
All problems (adverse events) related to a medicine or medical device used for treatment or in a procedure should be reported to the Medicines and Healthcare products Regulatory Agency using the ...
The New York Times29d
Foreign Aid Freeze Leaves Millions Without H.I.V. Treatment
H.I.V. treatment and services were funded through the President’s Emergency Plan for AIDS Relief, or PEPFAR, a $7.5 billion program that was frozen along with all foreign aid on Mr. Trump’s ...
Nature1mon
Salmonellae interplay with host cells
Salmonellae are globally important Gram-negative bacterial pathogens that infect a range of hosts and cause several diseases, including gastroenteritis and typhoid fever. Orally ingested bacteria ...
BMJ1mon
Incidence and aetiology of infant Gram-negative bacteraemia and meningitis: systematic review and meta-analysis
Background One in six infant deaths worldwide are caused by invasive bacterial infections, of which a substantial but unquantified proportion are caused by Gram-negative bacteria. Methods We conducted ...
The New England Journal of Medicine1mon
Isoproterenol in the Treatment of Shock Due to Bacteremia with Gram-Negative Pathogens
Treatment was divided into 3 stages ... Urinalysis revealed a ++ test for protein, with pus cells and numerous gram-negative rods in the sediment. The blood urea nitrogen was 47 mg.
Frontiers5mon
Bioinformatic analysis reveals the association between bacterial morphology and antibiotic resistance using light microscopy with deep learning
Although it is well known that the morphology of Gram-negative rods changes on exposure to antibiotics, the morphology of antibiotic-resistant bacteria in the absence of antibiotics has not been ...
Frontiers4y
AOA-2 Derivatives as Outer Membrane Protein A Inhibitors for Treatment of Gram-Negative Bacilli Infections
Data expressed as a percentage of cell viability. Similar results were observed with PAO1 and ATCC 25922 strains. Treatment of both strains with RW01 at the three concentrations increased ...