Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are ...

Researchers have identified how autophagy and chaperone-mediated autophagy (CMA) drive the unconventional secretion of PARK7, ...

The authors propose that the kinase MARK2 regulates the Golgi's reorientation towards the cell's leading edge through the regulation of microtubule binding protein CAMSAP2 and its binding to USO1.

Researchers have identified that the status of the T-cell Golgi apparatus is a key indicator of performance in cancer immunotherapy approaches. A group of researchers working at the Medical University ...

The Golgi apparatus modifies, sorts and packages proteins to be sent to their final destinations, whether that's within or outside of the cell. It's a core function, but little studied in the ...

Researchers investigating ways to reduce exhaustion in cancer-fighting T-cells found that the Golgi apparatus can be used as a simple marker -- more Golgi means a more robust cell. The Golgi ...

While the interplay between LDs and the Golgi apparatus has been recognized, their roles and underlying mechanisms remain poorly understood. Here, we reveal the role of Ras-related protein Rab-2A ...

Although recent studies have shown that Golgi-LC3 lipidation follows Golgi damage, its molecular mechanism and function under Golgi stress remain unknown. Here, by combining DLK1 overexpression as a ...

But I will address the latter by telling the story of a remarkably brilliant person, 1906 Nobel Prize-winner Camillo Golgi—who retained an incorrect notion for the rest of his life, despite the ...

After examining the cells of the cerebellum, the team discovered that two specific types of brain cell found in this area were particularly vulnerable to brain inflammation—the Golgi neurons and ...