Intriguingly, transplanted cells overexpressing the BAF component Baf60c/Smarca3b and Gata5 preferentially contribute to the embryonic zebrafish heart 12. Similarly, forced expression of Baf60c along ...

GATA5 mutations . Two heterozygous missense mutations in GATA5 were identified in two of 110 unrelated probands. The total population prevalence of GATA5 mutations based on the proband cohort was ...

Age-related Macular Degeneration and Central Serous Chorioretinopathy Have Overlapping Genetics —Using a meta-analysis and genome-wide association studies, 3 novel loci for central serous ...

However, vgll4l expression in mixl1/gata5 overexpressing embryos was not as profoundly reduced on Sox32 KD as was the case for eomesa/mixl1/gata5 overexpression. It is not completely clear whether ...

Scripts for making Figure 1-3 and Supplementary Figure 1-3. Input matrices can be found at ArrayExpress and processed Rdata can be downloaded at figShare. rmd folder contains the Rmarkdown files and ...

Introduction. GATA family includes six nuclear transcriptional factors sharing the ability to bind to the consensus DNA sequence T/A (GATA)A/G; of those, GATA4, GATA5, and GATA6 are involved in ...

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The gata5:lifeAct-EGFP only stains the apical brush border of the intestine. Total EECs number was assessed via counting RFP+ cell bodies. The number of EECs with intact apical protrusion was assessed ...

Endothelial-specific loss of GATA5 in mice leads to vascular endothelial dysfunction and hypertension by disrupting several pathways essential for proper endothelial signaling and homeostasis. 9 ...

GATA5 belongs to the GATA family of transcription factors characterized by highly evolutionarily conserved zinc-finger DNA-binding domains. 31,32 Studies have implicated a role of GATA5 during ...

Despite its high prevalence and economic burden, the aetiology of human hypertension remains incompletely understood. Here we identify the transcription factor GATA5, as a new regulator of blood ...