The interferon-induced GTPase GVIN1 prevents bacteria from spreading among cells by coating them and rendering them immobile.

Most of the cells in our bodies don't move—they stay where they're supposed to in service to our organs and biological ...

Scientists have identified the genetic mutation responsible for the ginger coloration in domestic cats —a phenomenon never ...

Johnson & Johnson bought the full rights to a rare disease gene therapy a few years ago, but now the Big Pharma may be experiencing buyer’s remorse. The treatment failed to improve the vision ...

Their patterning involves transitions between inactive cytosolic and active membrane-bound states, regulated by guanine nucleotide exchange factors (GEFs), GTPase-activating proteins (GAPs), and ...

The GTPase NRas pipeline drugs market research report outlays comprehensive information on the GTPase NRas targeted therapeutics, complete with analysis by indications, stage of development, mechanism ...

Drp1 (dynamin-related protein 1), a large GTPase, mediates the increased mitochondrial fission, which contributes to hyperproliferation of pulmonary artery smooth muscle cells in pulmonary arterial ...

has shown that two GTPase hydrolase enzymes (Rab5 and EEA1) function effectively as a reversible molecular motor. Although much of the heavy lifting in the body has shifted to use ATP with ATPases ...

Astellas Pharma Inc. has described new quinazoline GTPase KRAS (G12D mutant) degradation inducers reported to be useful for the treatment of pancreatic cancer. An exemplified compound degraded ...

High levels of active SOS compete with sotorasib for target engagement. Abbreviations: DUSP, dual-specificity phosphate; ERK, extracellular signal-regulated kinase; GAP, GTPase-activating protein; GEF ...