ABSTRACT: Introduction: Genetic polymorphisms of certain classes of glutathione S-transferase (GST), the enzyme responsible for the biotransformation of drugs and xenobiotics, have been associated ...

This study aimed to evaluate the influence of genetic variants of GST (GSTT1/GSTM1) and their association with the exposure to environmental toxins in PD patients. We studied 254 patients with PD and ...

Genotypes of glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) were investigated on extracted genomic DNA of 37 exposed workers using the polymerase chain reaction based method. In exposed group ...

A known complication of cisplatin is acute kidney injury (AKI). Deletion polymorphisms of GSTM1 and GSTT1, members of the glutathione S-transferase family, are common in humans and are presumed to be ...

O presente estudo teve como objetivo investigar a relação entre polimorfismos em genes desintoxicantes (GSTM1, GSTT1 e GSTP1) e sua associação com câncer colorretal (CCR) em tabagistas da etnia ...

Summary: A new study identifies the Gstt1 gene as crucial for metastatic cancer cell growth. Researchers found that silencing Gstt1 in metastatic cells prevents their spread. This gene helps cancer ...

The glutathione S-transferase Gstt1 drives survival and dissemination in metastases. Nature Cell Biology , 2024; DOI: 10.1038/s41556-024-01426-7 Cite This Page : ...

In this study, we investigated the association between the polymorphism of GSTM1 and GSTT1 genes and the risk of HIV-1 disease progression. Methods: We conducted a case-control study including 313 ...

The short answer here is no, you absolutely don’t need to play the first two Baldur’s Gate games to play 3. Despite being the third game in a dense, lore-filled franchise, Baldur’s Gate 3 is ...

Through a protein interaction network (PPI) and a LASSO regression analysis, a total of two Hub genes were identified, namely GPX3 and GSTT1, which were validated through external validation sets and ...

Fludarabine and cyclophosphamide combination in the treatment of patients with indolent non-follicular B-cell non-Hodgkin’s lymphomas. Results of a phase II trial of the Gruppo Italiano per lo Studio ...