ABSTRACT: Introduction: Genetic polymorphisms of certain classes of glutathione S-transferase (GST), the enzyme responsible for the biotransformation of drugs and xenobiotics, have been associated ...

A known complication of cisplatin is acute kidney injury (AKI). Deletion polymorphisms of GSTM1 and GSTT1, members of the glutathione S-transferase family, are common in humans and are presumed to be ...

O presente estudo teve como objetivo investigar a relação entre polimorfismos em genes desintoxicantes (GSTM1, GSTT1 e GSTP1) e sua associação com câncer colorretal (CCR) em tabagistas da etnia ...

No significant financial relationships to disclose. This is an ASCO Meeting Abstract from the 2006 ASCO Annual Meeting. This abstract does not include a full text component.

Objective: To assess if the genotype of the glutathione S-transferase M1 (GSTM1) enzyme and its GSTM1 null polymorphism can influence the response to chemotherapeutic treatment of advanced ovarian ...

Methods: Gstm1 KO male mice (12 weeks old) on 129S6 background were used for the study. After a 2-week training period, baseline systolic blood pressure (SBP) was measured by tail cuff daily for 2 ...

Objectives: To examine whether the interaction of polymorphism of GSTM1 gene and occupational sunlight exposure modulate the risk of cataract. Methods: Blood samples from 95 subjects with cataract and ...

Backgrounds: Compared with previously published meta-analyses, this is the first study to investigate the combined effects of glutathione-S-transferase polymorphisms (GSTM1, GSTT1 and GSTP1 IIe105Val) ...

To investigate whether null variants of Glutathione S-transferase Mu 1 (GSTM1) and GST Theta 1 (GSTT1) in infants and mothers, as well as maternal exposures to environmental factors, contribute to the ...

The first act of Baldur's Gate 3 has arrived in early access, and developer Larian Studios is already hard at work making improvements to it. Small adjustments are made to Baldur's Gate 3 just ...

Glutathione S-transferase mu-1 (GSTM1) is an enzyme that plays a role in ridding the body of toxins and combatting oxidative stress. Many individuals carry a variant in the GSTM1 gene that ...

Glutathione S-transferase mu-1 (GSTM1) is an enzyme that plays a role in ridding the body of toxins and combatting oxidative stress. Many individuals carry a variant in the GSTM1 gene that ...