AP sites exist in equilibrium between a closed‐ring furanose and an open‐ring aldehyde form. The latter is prone to undergo spontaneous β‐elimination, resulting in strand scission and DNA ...

Although this would make the C2-OH less well coordinated, this reasoning is consistent with biochemical analysis. Specifically, GLUT5 can transport 2,5-dihydromannitol with similar kinetics to ...

While ribose primarily exists as a pyranose in solution, the furanose is the preferred substrate in the ensuing phosphorylation by the ribokinase RbsK (Sigrell et al., 1998). Thus, the intracellular ...

In contrast to acylsucroses extracted from S. lycopersicum M82, which have an iC5 acyl chain at the R 3′ position of the furanose ring, some S. habrochaites accessions produce acylsucroses with long ...

Specifically, experimental and theoretical investigations reveal that glucose partitions into the zeolite in the pyranose form, ring opens to the acyclic form in the presence of the Lewis acid center, ...

The gemcitabine sugar may be more flexible than the ara-C sugar because disfavorable stereo-electronic forces can arise from interaction of either fluorine substituent relative to the furanose O4′.

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