genetic and molecular bases of neurodegenerative disorders have led to a shift away from traditional nomenclatures of clinical syndromes. Historically, frontotemporal lobar degeneration (FTLD ...

At least 18 different disorders can be distinguished on pathological and genetic grounds ... prominent apraxia (corticobasal degeneration), parkinsonism (frontotemporal lobar degeneration ...

Conversely, those with frontotemporal lobar degeneration (FTLD) showed milder effects, possibly due to a stronger genetic component in this condition. The research team, led by Dr. Agustín Ibanez ...

While less common, tissues from patients with genetic causes of Alzheimer's disease, Parkinson's disease, frontotemporal dementia and ALS also are shared with research investigators. The ...

Corticobasal Degeneration Market Outlook 2025-2035 ... The aging brain, by its nature, is more vulnerable to these conditions. Genetic predisposition and environmental exposures are compounded to ...

ALS presents with diverse clinical manifestations and genetic backgrounds, complicating the development ... a central regulator of nerve cell degeneration. SARM1 activation leads to axonal ...

Researchers discovered that nearly 70 per cent of suspected frontotemporal dementia patients ultimately did not have the disease in a study aimed at identifying factors that contribute to misdiagnosis ...

University of Queensland researchers discovered that nearly 70 per cent of suspected frontotemporal dementia patients ...

Researchers have uncovered the mechanism underlying frontotemporal lobar degeneration (FTLD) caused by variants in the valosin-containing protein (VCP) gene. Their study, which used a fruit fly ...

Scientists are urgently seeking fluid biomarkers for frontotemporal dementia, the most common dementing illness among 40- and 50-year-olds. Two large collaborations studying genetic FTD cohorts have ...