Oxysterols are a class of molecules derived from cholesterol via oxidation or as byproducts of cholesterol synthesis. Despite ...

A multi-omics study reveals that impaired branched-chain amino acid (BCAA) catabolism is a key driver of sarcopenia, suggesting it as a potential therapeutic target.

It usually happens over a long period, often due to hepatitis, alcohol use disorder, or metabolic dysfunction-associated steatotic liver disease (MASLD), formerly called non-alcoholic fatty liver ...

Dietary measures and medications may help reduce uric acid and manage gout. Gout can occur when blood uric acid levels are too high, causing crystals to form in the toes, feet, and other joints.

This method can also be employed for the fractionation of lipid subclasses ... The lipid species that were analyzed include non-hydroxylated fatty acid/sphingosine (NS) class of sphingolipids, with an ...

Myristic acid (MA) is the only donor for protein myristoylation. To assess the impact of SLC25A1 and ACLY knockdown on MA availability, we quantified MA levels in cells using LC-MS/MS. Our analysis ...

Uric acid is a waste product found in urine. If your body makes too much or doesn't eliminate enough of it, uric acid levels can become too high—a condition known as hyperuricemia. High uric acid ...

Fatty acids are organic acids with at least one carboxyl (-C(=O)OH, -COOH or -CO2H) group and a long carbon chain that can be joined by double bonds, as in unsaturated fatty acids, or single bonds ...

Xiamen Cell Therapy Research Center, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen 361003, China ...

Despite its resilience, it can still be affected by conditions like fatty liver disease, one of the most common liver disorders. It develops when too much fat builds up in the liver cells, which may ...