BMP/FGF relationship is responsible for promoting bone regeneration and bone loss. The aim of this study was to analyze the correlation between BMP4, FGF3, FGF10 and FGFR1 genes and peri-implant bone ...

We have identified FGF3 as a candidate for this signal: FGF3 is a target of β‐catenin, and it can rescue inhibition of MAPK activation by dnXTCF. We do not know, however, whether the inductive signal ...

Specifically, we detected amp of FGF3 (n=24, 52%), FGF4 (n=23, 50%), FGF19 (n=17, 37%), FGFR1 (n=18, 39%). In patients with alteration of the FGF/R axis, the most frequent aberrations were CCND1 (n=22 ...

The heart is the first organ to form during embryonic development. Given the complex nature of cardiac differentiation and morphogenesis, it is not surprising that some form of congenital heart ...

There were 116 pts in cluster 2 (C2) characterized by PIK3CA amplification (amp). Cluster 3 (C3) had 33 pts and was characterized by gene amp of CCND1, FGF3, FGF4, and FGF19. Cluster 4 (C4) was ...

aKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Gastrointestinal Oncology, Peking University Cancer Hospital and Institute, Beijing, China ...

In this study, we observed that FGF3/4/19/CCND1 amplification strongly promoted gefitinib resistance in vitro and in vivo. The combination of LY2874455 and abemaciclib was necessary to completely ...

The manuscript by Thiery et al brings valuable results for understanding the developmental strategies of signalling centres during shark teeth appearance. We believe that it will bring new insight ...

Olaparib and pembrolizumab appear to be a safe and tolerable combination therapy for patients with advanced cholangiocarcinoma. The use of olaparib (Lynparza) and pembrolizumab (Keytruda) was ...

Four candidates are competing for a four-year term as Missouri’s lieutenant governor, the state’s second highest office. The lieutenant governor is the ex-officio president of the Missouri ...

Most of the induced breast tumors are mainly at wnt1 and fgf3 sites by MMTV infection in wild-type mice (15, 16). Furthermore, FGFR2 is also a common MMTV insertion site (14). High FGFR expression can ...