Future Oncol. 2012;8(11):1427-1442. In the following sections we discuss the different constituents of the microenvironment and how they are influenced and modified by the tumor cells. Taken ...

intermedia venom upon extracellular matrix constituents such as fibronectin, fibrinogen, entactin and heparan sulfate proteoglycan, besides the disruptive activity of the venom on ...

1 Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC, Canada 2 Institut für Allgemeine und Spezielle Zoologie, Justus-Liebig-Universität Giessen, Giessen, ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The tight junction (TJ) in epithelial cells is ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The establishment and maintenance of ...

1 Division of Surgery and Interventional Science, Department of Targeted Intervention, Centre for 3D Models of Health and Disease, University College London, London, United Kingdom 2 Faculty of ...

and a complex consisting of the proteins laminin and entactin (LN/ET complex), all of which are known are expressed in the embryonic heart, are necessary and sufficient to enable structural ...

We next tested whether laminin alone, in combination with entactin, or the combination of laminin–entactin–collagen would be sufficient to recapitulate the effect of dissolved Matrigel.

During the development of an embryo, a group of proteins known as growth factors stimulate cells to divide and direct how organs and limbs form. One family of growth factors called bone morphogenetic ...

These cells were cultured in a 3D gel, the Matrigel matrix, which contains laminin, collagen IV, proteoglycan, entactin, and growth factors — all components of an extracellular matrix into which ...