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† † Department of Pharmacognosy and § Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, University, Mississippi 38677, United States Tel: (662) 915-7026.
Cape Town - The man who brutally murdered 32-year-old Lynette Volschenk in 2019 was referred for psychiatric evaluation by the Cape High Court on Wednesday. Kyle Ruiters was convicted on charges ...
"We discovered an unexpected method of control: eEF2K (eukaryotic elongation factor-2 kinase) controls processing bodies as well as ribosomes. It seems to promote an inactive state of the ribosome ...
There is a complex set of protein factors including EF-Tu/eEF1A, EF-G/eEF2, EF-P/eIF5A, and SelB/EFsec (Table 1), involved in translation elongation. Although the fundamental mechanism of the ...
In addition to the conserved translation elongation factors eEF1A and eEF2, fungi require a third essential elongation factor, eEF3. While eEF3 has been implicated in tRNA binding and release at the ...
Among the observed structural changes, ubiquitin mediates the destabilization of proteins in the 60S P-stalk and in the 40S beak, two binding regions of the eukaryotic elongation factor eEF2. These ...
In order to examine the molecular pathways downstream of dopamine receptors, we used genetic, pharmacologic, biochemical, and imaging methods, and found that activation of dopamine receptor D1 but not ...
We observe a persistent elevation in protein synthesis within 5 minutes of mGluR activation and a robust inhibition of the same within 2 minutes of NMDAR activation, assessed by the phosphorylation ...
The first comprises ribosomes sequestered with elongation factor 2 (eEF2) by SERPINE mRNA binding protein 1 (SERBP1) occupying the ribosomal mRNA entrance channel. The second type are translationally ...