Variants found by OGM but missed by standard of care included the EWSR1::ETV1 fusion, which is a key molecular hallmark of clear cell sarcoma and helps to differentiate it from other soft tissue ...

The following is a summary of “CircPRELID2 functions as a promoter of renal cell carcinoma through the miR-22-3p/ETV1 cascade,” published in the May 2024 issue of Urology by Lin et al. Emerging ...

One of our teams discovered a mutation that drives bowel cancer's development by causing higher levels of the gene ETV1. We hope that patients with this mutation will soon benefit from drugs targeting ...

Depression of ETS variant 1 (ETV1) levels inhibited the progression of gastrointestinal stromal tumor (GIST) cells, according to a study published in the Journal of Clinical Biochemistry and Nutrition ...

The work both validates previous findings and provides new data that support a compelling overall conclusion that combined ERF and CIC loss promotes prostate tumorigenesis by increasing expression of ...

Results: Our findings indicated that the upregulation of PEA3 members including ETV1 and ETV5 was positively associated with poor prognosis in CRC patients. Meanwhile, ETV1 and ETV5 may play ...

The median overall survival was not reached yet. What about these results highlight the importance of GIST lineage dependence on ETV1 and KIT? One of the things we think it validated from preclinical ...

The purpose of this study is to characterize the response of the ETV1 (ETS translocation variant 1) signaling axis in the LA during cardiac pressure overload in humans and mouse models and explore the ...

Another protein, the transcription factor ETV1, was also found to play a role in tumorigenesis alongside KIT in gastrointestinal stromal tumors. Conflicting evidence suggested that ETV1 might be a ...