Researchers capture first-of-its-kind video of dynein–Lis1 protein interaction, supporting future drug development for neurological disorders. Our cells rely on microscopic highways and specialized ...

For example, the dysfunction of Lis1, a partner protein to the motor protein dynein, can lead to the rare fatal birth defect lissencephaly, or “smooth brain,” for which there is no cure. But ...

Our goal is to reveal how the distinct motors myosin, dynein and kinesin coordinate to handover the endosome from the actin to the microtubule network, ensuring precise positioning and timely cargo ...

Jess Thomson is a Newsweek Science Reporter based in London UK. Her focus is reporting on science, technology and healthcare. She has covered weird animal behavior, space news and the impacts of ...

A mechanism of dynein-powered metastatic locomotion has been identified using soft tissue models, revealing a new clinical target for breast cancer treatment. New research led by Penn State (PA, USA) ...

Dynein is composed of two heavy chains (blue), two intermediate chains (yellow), four light intermediate chains (green) and several light chains, including DYNLRB1 (orange). The Molecular ...

Now, researchers from Pennsylvania State University (Penn State) have discovered that a protein called dynein is indispensable to the process of metastasis in breast cancer, providing a new ...

The discovery, showing that a motor protein called dynein powers the movement of cancer cells in soft tissue models, offers new clinical targets against metastasis and has the potential to ...

Recently, we showed that disruption of the microtubule network, with colchicine, or inhibition of the microtubule motor protein, dynein, with ciliobrevin D, enhanced the membrane abundance and ...