Previous research has shown that aberrant sphingolipid metabolism, which is evidenced by elevated levels of circulating ceramide, is associated with poor prognosis in patients with prostate cancer (PC ...

It builds upon existing research by investigating the endogenous complexes of DVL2 using ultracentrifugation and contrasting them with DVL1 and DVL3 behavior. The study identifies a DVL2-specific ...

TTLL11 efficiently polyglutamylates the Wnt signaling protein Dishevelled 3 (DVL3), thereby changing the interactome of DVL3. Polyglutamylation increases the capacity of DVL3 to get phosphorylated, to ...

aDepartment of Pathology, College of Medicine, The Catholic University of Korea, 505 Banpo-dong, Seocho-gu, Seoul 137-701, South Korea bFunctional RNomics Research Center, College of Medicine, The ...

This study identified Wnt7b as a noncanonical Wnt (ncWnt) ligand acting in concert with Wnt5a to promote elongation and outgrowth of multiple tissues, including the anterior–posterior body axis, ...

aHospital of Stomatology, Sun Yat-sen University, Guangzhou 510060, China bGuangdong Provincial Key Laboratory of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou 510080, ...

Department of Biochemistry, Zunyi Medical University, Zunyi, China. Figure 3. The role of Wnt/planar cell polarity signaling in neural tube closure. (a) The PCP complex in the process of CE is ...

Page 13218, second paragraph, left column: change third and fourth sentences to “In addition, the gene expressions Prkcg, Ccnd1, Prkaca, Sfrp2, Porcn, Dvl3, Fzd7, Sfrp4, Gsk3β, Ror2, LRP5, and Wnt10b ...

Capture of molecular interaction data will contribute to the expansion and development of the existing molecular interaction networks and advance our knowledge about interactions within the ...

The top 10 frequent alterations were PIK3CA, FGF3, FGF19, FGF4, DVL3, P3H2, GNB4, COL22A1, COL14A1, and PLOD2. Conclusion: This study showed the critical role of stemness-related genes in HNSCC.