Gene Hackman and Betsy Arakawa Hackman's last few days were retraced by New Mexico authorities as they worked backward to solve the mystery of their deaths. On Friday, officials revealed Gene's ...

Research indicates that this reprogramming process involves a complex regulatory network, featuring key genetic elements such as the Zscan4 gene, endogenous retrovirus MERVL, transcription factor Dux, ...

Using proximal labeling proteomics, the authors identified candidate proteins that are implicated in Dux-mediated gene activation. They were able to showcase that the C-terminal repeat 3 binds to some ...

The DUX4 gene is found near the end of chromosome 4 in a region called D4Z4. Normally, DUX4 stays switched off in muscle cells, but in FSHD, it is switched on and abnormally produces a protein called ...

Gene therapies treat or prevent disease by tweaking the content or expression of cells' DNA. When you purchase through links on our site, we may earn an affiliate commission. Here’s how it works ...

SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Epic Bio, a biotechnology company developing therapies to modulate gene expression using compact, non-cutting dCas proteins, today announced a ...

SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)-- Epic Bio, a biotechnology company developing therapies to modulate gene expression using compact, non-cutting dCas proteins, today announced a ...

Epic Bio today announced a presentation on the company’s unique engineering platform, called the Gene Expression Modulation System (GEMS), at the co-hosted Solebury / BMO Fall Private Company Showcase ...

The gene knockdown by CRISPR–Cas9 was performed in our previous ... The 2C-like transition is initiated by the transcription factor Dux and is reversible. Our results indicate that Zfp281 specifically ...