Researchers at Vanderbilt University identified a molecular approach to extend the antidepressant effects of ketamine in mice by applying BCI, a compound that inhibits DUSP6 to sustain ERK pathway ...

“In CRC, higher levels of DUSP6 have been found in tumors, where it helps the cancer cells grow faster, spread more easily, and leads to poorer outcomes for patients,” said Associate Professor ...

The discovery, published in Nature Communications, sheds light on the role of Dual-Specificity Phosphatase 6 (DUSP6), a molecule that has been found to play a significant part in the aggressive ...

Tracking the path to MPN development -- and stopping it An earlier study by Oh's group identified a signaling molecule called DUSP6 as an important protein driving the progression of MPNs.

Their study, published in Nature Communications, has revealed that a molecule called Dual-Specificity Phosphatase 6 (DUSP6) plays a major role in helping CRC grow. The CRC cells with higher DUSP6 ...

Their study, published in Nature Communications, has revealed that a molecule called Dual-Specificity Phosphatase 6 (DUSP6) plays a major role in helping CRC grow. The CRC cells with higher DUSP6 ...

Studies have shown that DUSP6 plays an important role in the heart and diet-induced obesity. However, the role of DUSP6 in vascular disease is largely unclear. Our goal is to investigate whether DUSP6 ...

Introduction: Dual specificity protein phosphatase 6 (DUSP6) was recently identified as a key hub gene in a causal VGF gene network that regulates late-onset Alzheimer’s disease (AD). Importantly, ...

DUSP6 protein activity associated with awakening of the breast cancer cells A newly-published Finnish study provides important new insights into how breast cancer cells belonging to the HER2 ...

Focusing on phosphatases, expression of dual-specificity phosphatase DUSP6 was found inhibited in dormant cells, but strongly induced upon regrowth. DUSP6 expression also selectively associated with ...