Researchers identify a new player in human immunity that can go rogue and turn the immune system against the body’s own ...

Anti-CD20 mAbs were originally created to treat B cell proliferative diseases such as non-Hodgkin's lymphoma and chronic ...

CRIg, CR3, and CR4 facilitate phagocytosis and modulate the activation state ... complement can revolutionize the treatment of patients with overactive complement-mediated diseases. The authors ...

Triggering receptor expressed on myeloid cells 2 (TREM-2) modulates TLR4-mediated inflammation in bone marrow (BM)-derived macrophages but its function in liver injury is unknown. Here we hypothesised ...

CRP provides a link between the innate and adaptive immune systems by activation of complement and interaction with Fcγ receptors. Basal levels of CRP in the serum are influenced by polymorphisms ...

Several leukocytes perform phagocytosis, which is described in more detail below. The innate immune system also employs some important chemical defenses using interferons and complement proteins which ...

Shaanxi Key Laboratory of Macromolecular Science and Technology, Xi’an Key Laboratory of Hybrid Luminescent Materials and Photonic Device, MOE Key Laboratory of Material Physics and Chemistry under ...

Complement in mammalian plasma recognizes pathogenic, immunogenic and apoptotic cell surfaces, promotes inflammatory responses and marks particles for cell lysis, phagocytosis and B-cell stimulation.

The complement components C3 and C1q may induce phagocytosis ... The possible mechanism of P2Y6 receptor-mediated phagocytosis is related to myosin light chain kinase (84). After all, it indicates ...