Cohesin is a protein that forms a ring-shaped complex which wraps and alters the DNA molecule shape. It moves through the DNA ...

Cohesin is a protein that forms a ring-shaped complex which wraps and alters the DNA molecule shape. It moves through the DNA ...

Genomic DNA is assembled into chromatin by histones, and extruded into loops by cohesin. These mechanisms control important genomic functions, but whether histones and cohesin cooperate in genome ...

A host of ring-shaped cohesin molecules holds the two threads together. "When a cell is about to divide, the cohesin rings open, and the arms of the DNA come apart. The rings in the middle of the DNA ...

The team studied a key component of a ring-shaped protein complex, called cohesin, which is known to play a key role in holding chromosomes together during cell division. Dr Rowland said ...

In 2018, Dekker and his group were the first to visualise how SMC protein complexes such as condensin and cohesin extrude loops in DNA. #2 CTCF flags have a direction and determine where a loop ...

A new role for cohesin in regulating alternative splicing has been identified, providing insights into splicing mutations in human disease. Cohesin is known to play a key part in transcription ...

Proper physiological functioning of any cell type requires ordered chromatin organization. In this context, cohesin complex performs important functions preventing premature separation of sister ...