Her father suggested going to see a medical professional. After several tests, doctors diagnosed Aubrie with CIC-DUX4 sarcoma cancer. “I couldn’t believe this was happening to her,” Peña said. Aubrie ...

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When young, sporty Esme Orike complained of a sore ankle, nobody would have guessed that within 18 months she would be dead from a rare, aggressive cancer. Esme, who lived in Southgate, died on ...

Esme, who lived in Southgate, died on September 5 aged just 13 from CIC-DUX4 sarcoma, a rare, aggressive soft tissue tumour that mainly occurs in children and young adults. Mum Charlotte Adlam ...

and concluded that CIC-DUX4 fusion transcripts induced up-regulation of multiple tumor enhancer activator 3 (PEA3/ETV4/E1AF) family genes, which could express ETV4 and WT1. All CIC-NUTM1 sarcomas ...

Fulcrum exclusively in-licensed losmapimod from GSK following Fulcrum’s discovery of the role of p38α/β inhibitors in the reduction of DUX4 expression and an extensive review of known compounds.

My research (internship) is focused on fusion detection in RNA-seq with short read illumina dataset. One of the hardest fusion to find is CIC-DUX4 in our dataset and I used STAR for alignment. I used ...

And their prognosis is quite different. The patients who get them are different. Take one example, CIC-DUX4 sarcoma, where the patients are older, it's usually a soft tissue tumor instead of a ...

"They never catch it this early," Chelsey said. Layla was diagnosed with a very rare cancer called CIC-DUX4 Rearranged Roundcell Sarcoma. It's a form of sarcoma that doctors say presents similar ...