Researchers have uncovered a stealth survival strategy that melanoma cells use to evade targeted therapy, offering a ...

Although cystic fibrosis is a single gene mutation, there are more than 1,000 different ways the CFTR gene can mutate in ...

Adverse genetic mutations can cause harm and are due to various circumstances. "Jumping genes" are one cause of mutations, ...

New imaging reveals a built-in safeguard that allows B cell populations to rapidly expand in germinal centers without introducing deleterious mutations.

A vaccine's ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance. Upon exposure to a ...

It’s time for researchers to reconsider the current paradigm of cancer as a genetic disease, argued Sui Huang from the ...

In a recent essay, scientists challenge the prevailing genetic-focused model of cancer, advocating for a shift towards more ...

It's time for researchers to reconsider the current paradigm of cancer as a genetic disease, argued Sui Huang from the Institute for Systems Biology, USA, and colleagues in a new essay published March ...

The PIK3CA gene gives instructions to make a protein that’s important for many cell functions. A PIK3CA mutation isn’t inherited – you can’t pass it down to your children. Instead ...

The BRAF mutation affects a small percentage of non-small cell lung cancer (NSCLC) cases, making the cancer more difficult to treat. In recent years, advances in treatment have helped to improve ...

So, this is how osimertinib will be used in the NHS. People with EGFR mutation-positive NSCLC whose tumours have been surgically removed (complete resection) have the option of then having ...

An EGFR gene mutation is one of the biomarkers a doctor often tests for after confirming a diagnosis of non-small cell lung cancer (NSCLC). Biomarkers can help guide treatment. EGFR mutations ...